A Role for Progesterone in Breast Cancer Treatment?

New research sheds light on the role of progesterone in hormone receptor-positive breast cancer.Back in August 2015, I wrote about an article in the journal Nature on some interesting new discoveries about the role of the hormone progesterone in hormone receptor-positive breast cancer.

The research suggested that adding progesterone to standard treatment with tamoxifen or an aromatase inhibitor could increase the effectiveness of treatment for this subtype of breast cancer, while possibly also lowering toxicity.

Cancer Research UK reports that these findings are now going to be investigated in three clinical trials that are set to begin.  Continue reading

5 Cancer Research Stories Worth Following – Summer 2016

Cancer research stories worth following this summer include a study on extending the use of aromatase inhibitors in the treatment of hormone receptor-positive breast cancer.What’s exciting in cancer research right now? In this post, I’ll review several of the most interesting cancer research stories that have been in the news this summer.

These are a few of the recent stories that seem to have the greatest potential impact, at least from my perspective, and that I know I’ll want to follow as they develop further.

Stories worth following include several studies presented at the annual meeting of the American Society of Clinical Oncology (ASCO) in June.  Among those were a study on extending the use of aromatase inhibitors in breast cancer treatment; findings that a web app boosts survival for patients with lung cancer; and, research on the use of a “biosimilar” treatment that can substitute for the breast cancer drug Herceptin. Continue reading

San Antonio Breast Cancer Symposium 2015: “These Data Belong to Our Patients”

The San Antonio Breast Cancer Symposium highlights the latest findings in breast cancer research such as efforts to develop more tailored treatments for patients.Attending the annual San Antonio Breast Cancer Symposium–as I did again this year–is an opportunity to hear directly from researchers about some of the latest findings in breast cancer research. It’s also a window into new directions that breast cancer research is going and what we may be hearing more about over the next few years.

There’s been a lot of hype lately about precision medicine. But in breast cancer at least, we really don’t yet have true precision medicine for most patients. But there are signs that’s starting to change. Continue reading

Hormone Receptor-Positive Breast Cancer: A Look At New Research Findings

New research sheds light on the role of progesterone in hormone receptor-positive breast cancer.A recent article in the journal Nature describes some interesting new discoveries that have been made about the role of the hormone progesterone in hormone receptor-positive breast cancer.

The role of progesterone and its receptor in breast cancer has not been well understood. And there has been some controversy about the value of this biomarker in selecting treatment for patients.

The study results, if confirmed, could potentially lead to improved treatment options for women with this common sub-type of breast cancer. Continue reading