Targeted Treatments for Hormone Receptor-Positive Breast Cancer

Targeted treatments for hormone receptor-positive breast cancer - stories we're following this year.One of the stories that has stood out over the last few years in breast cancer treatment was the FDA’s approval in 2015 of the drug palbociclib (Ibrance) for treatment of hormone receptor-positive metastatic breast cancer.

This year, there have been several new developments in targeted therapies for hormone-receptor positive breast cancer. Continue reading

Breast Cancer Treatment: The TAILORx Clinical Trial

TAILORx clinical trial findings will help personalize breast cancer treatment decisions.Earlier this month, the long-awaited results of the TAILORx clinical trial were announced.

The findings from this study are important for early stage breast cancer patients with hormone receptor-positive breast cancer. The study results are expected to assist many patients in this group in determining whether chemotherapy should be part of their treatment. Continue reading

Metastatic Breast Cancer: Learning About Innovative Research Approaches

Researchers are using genomic studies to develop better treatments for metastatic breast cancer.In a recent post, we looked at highlights of a major report on the status of metastatic breast cancer care and research. That report notes that progress against MBC has slowed and, over the past decade, only about 7% of research publications about breast cancer have been specifically about metastatic breast cancer. It also talked about several things that need to be done to accelerate progress and offered some hope that we are beginning to move in the right direction.

Shortly after writing that post, I attended an event where I learned about some fascinating MBC research that is going on now. The event was the 2016 Advocate Leadership Summit organized by the National Breast Cancer Coalition.

I’ll share here a few of my impressions from parts of the program that focused specifically on MBC research. Videos of these sessions are now available on the NBCC website. Continue reading

How Could a Blood Test Be Used Soon in Breast Cancer Care?

Can we detect breast cancer with a blood test or liquid biopsy?We’ve heard a lot in the news over the last year about how researchers are working to develop a blood test to detect cancer, sometimes referred to as a “liquid biopsy”.

What should we make of all this? A blood test, whether for early detection or to aid in treatment and monitoring, would be a wonderful development. But how close are we really?

As I headed to San Antonio for the annual Breast Cancer Symposium in December, I wondered what we might hear there about progress toward a liquid biopsy for breast cancer. I’ve shared some highlights from the Symposium in a recent post. In this post, I’ll share my impressions from the Symposium on where things stand with work toward a liquid biopsy for breast cancer. Continue reading

Hormone Receptor-Positive Breast Cancer: A Look At New Research Findings

New research sheds light on the role of progesterone in hormone receptor-positive breast cancer.A recent article in the journal Nature describes some interesting new discoveries that have been made about the role of the hormone progesterone in hormone receptor-positive breast cancer.

The role of progesterone and its receptor in breast cancer has not been well understood. And there has been some controversy about the value of this biomarker in selecting treatment for patients.

The study results, if confirmed, could potentially lead to improved treatment options for women with this common sub-type of breast cancer. Continue reading

San Antonio Breast Cancer Symposium 2014: Where Is Research Headed?

The 2014 San Antonio Breast Cancer Symposium highlighted potential new treatment strategies that are opening up as a result of advances in understanding of cancer biology.Innovative new approaches to breast cancer treatment that were featured at the 2014 San Antonio Breast Cancer Symposium could eventually have a big impact on the way breast cancer is treated.

Potential new treatment strategies are opening up as a result of recent advances in knowledge of cancer biology as well as improved understanding of how our immune system functions.  Technological advances are playing a big role too. Continue reading